The Positive Impact of Exercise for Patients with Metastatic Breast Cancer

The Challenges of Living with Metastatic Breast Cancer

Metastatic breast cancer, also known as Stage IV breast cancer, occurs when the disease has spread to other parts of the body. While treatments have improved survival rates, patients often face persistent symptoms such as fatigue, pain, and shortness of breath. These challenges significantly impact daily life, affecting physical health, mental well-being, and social interactions.

The PREFERABLE-EFFECT trial addressed these challenges by examining the role of exercise as a complementary approach to traditional cancer treatments. By providing patients with tools to manage their symptoms, the study aimed to enhance their ability to lead active and fulfilling lives despite their diagnosis.

The Design and Findings of the PREFERABLE-EFFECT Study

The PREFERABLE-EFFECT trial involved 357 participants, including two men, with metastatic breast cancer. The study divided patients into two groups: one received standard care with exercise advice, while the other participated in a structured nine-month exercise program. This program included strength, balance, and cardiovascular training, guided by oncological physical therapists.

The results were remarkable. Patients in the exercise group reported significant improvements in fatigue, pain, and overall quality of life compared to the control group. They also experienced enhanced endurance and reduced shortness of breath. These findings emphasize the value of tailored exercise regimens in helping patients cope with the physical and emotional burdens of their condition.

Overcoming Barriers to Exercise

For many patients, the idea of exercising while dealing with cancer symptoms can seem daunting. Common concerns include fear of increased pain, fatigue, and physical limitations. However, the study showed that participants who engaged in regular exercise felt better and more energized after their workouts.

The program’s success was partly attributed to its accessibility and personalized approach. Patients trained close to home and often in groups, fostering a sense of community and support. The guidance of trained physical therapists ensured that exercises were safe, effective, and adapted to individual needs. This personalized approach helped participants overcome barriers and maintain their commitment to the program.

The Long-Term Benefits of Physical Activity

One of the most encouraging outcomes of the PREFERABLE-EFFECT study was the sustained motivation among participants to continue exercising beyond the trial period. By integrating physical activity into their routines, many patients experienced lasting benefits, including improved strength, better mood, and enhanced overall well-being.

The researchers also hypothesized that exercise might reduce inflammation levels in the body, contributing to its positive effects. Ongoing analysis of blood samples collected during the study aims to explore these mechanisms further, potentially paving the way for new insights into the biological benefits of physical activity for cancer patients.

Expanding the Scope of Exercise in Cancer Care

While the PREFERABLE-EFFECT trial focused on breast cancer, the findings have implications for other types of metastatic cancers. Tailored exercise programs could benefit patients facing different symptoms and treatment side effects, offering a holistic approach to improving quality of life.

Encouraged by the success of the initial study, researchers are now launching PREFERABLE II, a follow-up project that will offer online exercise programs to cancer survivors. This initiative aims to reach more patients and further explore the role of physical activity in reducing long-term treatment side effects. By integrating exercise into standard cancer care, healthcare providers can empower patients to take an active role in their recovery and overall well-being.

From Ecomhao